Affinity DataIC50: 0.700nMAssay Description:Inhibition of CDK1/cyclinB (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scinti...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scinti...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences Limited
Curated by ChEMBL
Piramal Life Sciences Limited
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair